it is sure possible to just delete the font file from the font folder as long you have adequate permissions.
But I have no idea if the font is really "uninstalled" after that?!
I've tried with rev "delete" command & it failed. Then tried with cmd command (i.e. "cacls fontname.ttf /grant Administrators:F" then del command) but also failed.
Searched in google for vbscript but not found the exact one.